Showing posts with label calreticulin. Show all posts
Showing posts with label calreticulin. Show all posts

Friday, July 13, 2018

Cancer cells can treat tumors

Cancer cells can treat tumors.
New enquire suggests that many cancer cells are equipped with a class of suicide pill: a protein on their surfaces that gives them the aptitude to turn an "eat me" gesture to immune cells. The dispute now, the researchers say, is to feature out how to coax cancer cells into emitting the notify rather than a dangerous "don't eat me" signal bronovil. A about published online Dec 22 2010 in Science Translational Medicine reports that the cells stir out the enticing "eat me" notable by displaying the protein calreticulin.

But another molecule, called CD47, allows most cancer cells to evade undoing by sending the antithetical signal: "Don't tie on the nosebag me". In earlier research, Stanford University School of Medicine scientists found that an antibody that blocks CD47 - turning off the remarkable - could relieve wage war cancer, but mysteries remained reviews. "Many typical cells in the body have CD47, and yet those cells are not pretended by the anti-CD47 antibody," Mark Chao, a Stanford postgraduate undergraduate and the study's lead author, said in a university info release.